Long-term survival in patients older than 80 years hospitalised for heart failure. A 5-year prospective study.
Eur J Heart Fail
; 10(1): 78-84, 2008 Jan.
Article
en En
| MEDLINE
| ID: mdl-18096434
ABSTRACT
BACKGROUND:
Although heart failure (HF) is frequent in elderly patients, few studies have focused on patients older than 80 years.AIMS:
To evaluate the clinical features, treatment and long-term prognosis of HF in patients older than 80 years. METHODS ANDRESULTS:
Consecutive patients hospitalised for a first HF episode in the Somme Department (France) during 2000 were prospectively included. Of the 799 included patients, 305 (38%) were aged over 80 years. The elderly patients were mostly women with a high prevalence of atrial fibrillation, ischaemic and hypertensive heart disease. Ejection fraction (EF) was assessed in 68.5% of elderly patients and 61% had EF >or=50%. Angiotensin-converting enzyme inhibitors, beta-blockers, oral anticoagulants and statins were prescribed less frequently in elderly patients. The 5-year survival in elderly patients was 19%, dramatically lower than the survival of age- and sex-matched general population (48%). Cardiovascular causes were recorded in over 60% of deaths. On multivariable analysis, cancer, renal insufficiency, old myocardial infarction, diabetes, hyponatraemia and age were predictors of mortality in elderly patients. Reduced EF was a potent predictor of death (HR 1.72, 95%CI 1.24-2.37, p=0.001) in elderly patients.CONCLUSION:
Long-term prognosis in HF patients older than 80 years is poor, with a dramatic excess mortality compared to the elderly general population. Life-saving drugs are largely underused in elderly HF patients.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sobrevivientes
/
Insuficiencia Cardíaca
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur J Heart Fail
Asunto de la revista:
CARDIOLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Francia