One-pot synthesis of meso-formylporphyrins by S(N)Ar reaction of 5,15-disubstituted porphyrins with (2-pyridyldimethylsilyl)methyllithium.
Org Lett
; 10(4): 685-7, 2008 Feb 21.
Article
en En
| MEDLINE
| ID: mdl-18198882
ABSTRACT
A simple, one-pot procedure that converts 5,15-substituted porphyrins into the corresponding meso-formylated porphyrins has been developed. The method, based on a new synthetic concept for functionalized porphyrins utilizing the (2-pyridyldimethylsilyl)methyl group as a latent formyl functionality, affords the desired product in good yield and is especially appropriate for the direct formylation of free base porphyrins, which has never been achieved by known methods.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Compuestos Organometálicos
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Porfirinas
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Silicio
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Litio
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Japón