[The role of Stratus OCT in anti-VEGF therapy. Qualitative and quantitative assessment of neovascular AMD]. / Die Rolle des Stratus-OCT bei der Anti-VEGF-Therapie : Qualitative und quantitative Beurteilung bei neovaskulärer AMD.
Ophthalmologe
; 105(7): 650-5, 2008 Jul.
Article
en De
| MEDLINE
| ID: mdl-18273622
ABSTRACT
BACKGROUND:
The evaluation of OCT3 during anti-VEGF therapy.METHODS:
A total of 29 patients with choroidal neovascularization secondary to AMD received 3 intravitreal injections of ranibizumab. OCT examination and visual acuity testing (ETDRS) were performed before therapy onset, after 1 week and after 1, 2 and 3 months.RESULTS:
The central retinal thickness (CRT) was assessed correctly by OCT in 128 out of 145 measurements. There was a distinct (84%) but not significant correlation between decrease in central retinal thickness and increase in visual acuity. Incorrect retinal layer segmentation and inadequate CRT measurements were a significant technical limitation.CONCLUSION:
During anti-VEGF therapy, OCT allows documentation and quantification of morphologic retinal changes and in most cases also for an estimation of functional improvement.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Interpretación de Imagen Asistida por Computador
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Neovascularización de la Córnea
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Factor A de Crecimiento Endotelial Vascular
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Degeneración Macular
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Anticuerpos Monoclonales
Tipo de estudio:
Clinical_trials
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Diagnostic_studies
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Etiology_studies
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Prognostic_studies
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Qualitative_research
Límite:
Aged
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Female
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Humans
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Male
Idioma:
De
Revista:
Ophthalmologe
Asunto de la revista:
OFTALMOLOGIA
Año:
2008
Tipo del documento:
Article