Charge monitoring cell mass spectrometry.

ABSTRACT

An instrument to directly measure the charge carried by a cell or a microparticle as well as mass-to-charge ratio of the cell/microparticle was developed for rapid mass distribution measurement. A successful mass spectrum with a record high mass has been demonstrated. In this article, the details of the construction and operation of the charge monitoring cell mass spectrometer are reported. Examples are also given for demonstration and discussion.