Daptomycin exerts bactericidal activity without lysis of Staphylococcus aureus.
Antimicrob Agents Chemother
; 52(6): 2223-5, 2008 Jun.
Article
en En
| MEDLINE
| ID: mdl-18378708
ABSTRACT
The ability of daptomycin to produce bactericidal activity against Staphylococcus aureus while causing negligible cell lysis has been demonstrated using electron microscopy and the membrane integrity probes calcein and ToPro3. The formation of aberrant septa on the cell wall, suggestive of impairment of the cell division machinery, was also observed.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Staphylococcus aureus
/
Bacteriólisis
/
Daptomicina
/
Antibacterianos
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos