Allergic photocontact dermatitis due to suprofen. Photopatch testing and cross-reaction study.
Contact Dermatitis
; 25(4): 218-23, 1991 Oct.
Article
en En
| MEDLINE
| ID: mdl-1839262
ABSTRACT
We report 5 cases of photocontact dermatitis due to suprofen, a nonsteroidal anti-inflammatory drug introduced to the Japanese market in 1989, and available as a 1% ointment. The patients developed pruritic eczematous lesions after applying the ointment for from 2 weeks to 3 months. All 5 patients reacted positively to photopatch testing with ultraviolet A (UVA) and suprofen down to 0.1-0.01% pet., and 3 patients showed positive reactions with ultraviolet B (UVB) and suprofen down to 1.0-0.1%. Moreover, all patients showed a cross-reaction with tiaprofenic acid, which has a very similar chemical structure to suprofen. However, there was no cross-reaction between suprofen and ketoprofen. Prescribers should be aware of the existence of photocontact sensitivity due to these drugs.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastornos por Fotosensibilidad
/
Suprofeno
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Erupciones por Medicamentos
/
Dermatitis por Contacto
Límite:
Adolescent
/
Adult
/
Aged
/
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Contact Dermatitis
Año:
1991
Tipo del documento:
Article
País de afiliación:
Japón