Computer-assisted reading of DNA sequences.
Methods Mol Med
; 141: 177-97, 2008.
Article
en En
| MEDLINE
| ID: mdl-18453090
ABSTRACT
DNA sequencing is increasingly used in a range of medical activities involving DNA diagnostics and research. This is the result of improving technology and cheaper costs. Paradoxically, a greater demand for DNA sequencing has placed additional work on the laboratory because sequencing profiles must be checked visually despite the availability of informatics-based tools in interpreting DNA sequence traces. In this environment it is essential to have more sophisticated software that will allow the sites of known and unknown DNA variants to be quickly identified, as well as providing an objective assessment of quality for the DNA sequence generated. This chapter describes the Applied Biosystems SeqScape software program (version 2.5) and how it has assisted in the interpretation of DNA sequencing in a DNA diagnostic laboratory.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Procesamiento Automatizado de Datos
/
Análisis de Secuencia de ADN
Tipo de estudio:
Evaluation_studies
Límite:
Humans
Idioma:
En
Revista:
Methods Mol Med
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2008
Tipo del documento:
Article
País de afiliación:
Australia