The antioxidant properties of serum albumin.
FEBS Lett
; 582(13): 1783-7, 2008 Jun 11.
Article
en En
| MEDLINE
| ID: mdl-18474236
ABSTRACT
Free radicals are a normal component of cellular oxygen metabolism in mammals. However, free radical-associated damage is an important factor in many pathological processes. Glycation and oxidative damage cause protein modifications, frequently observed in numerous diseases. Albumin represents a very abundant and important circulating antioxidant. This review brings together recent insights on albumin antioxidant properties. First, it focuses on the different activities of albumin concerning protein antioxidation. In particular, we describe the role of albumin in ligand binding and free radical-trapping activities. In addition, physiological and pathological situations that modify the antioxidant properties of albumin are reported.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Albúmina Sérica
/
Depuradores de Radicales Libres
/
Radicales Libres
Límite:
Humans
Idioma:
En
Revista:
FEBS Lett
Año:
2008
Tipo del documento:
Article
País de afiliación:
Francia