The use of Affymetrix GeneChips as a tool for studying alternative forms of RNA.
Biochem Soc Trans
; 36(Pt 3): 511-3, 2008 Jun.
Article
en En
| MEDLINE
| ID: mdl-18481992
ABSTRACT
We are developing a computational pipeline to use surveys of Affymetrix GeneChips as a discovery tool for unravelling some of the biology associated with post-transcriptional processing of RNA. This work involves the integration of a number of bioinformatics resources, from comparing annotations to processing images to determining the structure of transcripts. The rapidly growing datasets of GeneChips available to the community puts us in a strong position to discover novel biology about post-transcriptional processing, and should enable us to determine the mechanisms by which some groups of genes make co-ordinated changes in their production of isoforms.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
ARN
/
Análisis de Secuencia por Matrices de Oligonucleótidos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Biochem Soc Trans
Año:
2008
Tipo del documento:
Article
País de afiliación:
Reino Unido