Self-test device for cytology and HPV testing in rural Appalachian women: an evaluation.
J Reprod Med
; 53(6): 441-8, 2008 Jun.
Article
en En
| MEDLINE
| ID: mdl-18664063
ABSTRACT
OBJECTIVE:
To determine the efficacy of a self-test device for obtaining vaginal/cervical samples for HPV DNA and cytologic testing. STUDYDESIGN:
We recruited 878 Appalachian women; 775 were able to submit a self-test sample and a provider-collected sample. Each specimen was assessed for cytologic abnormalities and for high-risk HPV infection.RESULTS:
Specimen adequacy 869 of 878 (99%) women had sufficient material for cytologic analysis in provider-collected samples compared to 771 of 775 (99%) self-collected specimens (p = NS). There was sufficient cellular material (DNA) for HPV testing in 724 of 834 (87%) provider-collected samples compared to 690 of 736 (94%) self-collected specimens (p <0.04). In the provider-collected samples, 654 of 869 (75%) women had endocervical cells compared to 103 of 771 (13%) self-collected specimens (p <0.001). HPV assessment 142 (19%) had high-risk HPV DNA detected. Of those women, 28 (20%) had HPV infection detected on the provider-collected specimen only, 51 (36%) on the self-collected specimen only, and 63 (44%) had HPV DNA on both specimens.CONCLUSION:
Our device is sufficient to obtain an adequate number of epithelial cells for cytologic and HPV testing.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Frotis Vaginal
/
Tamizaje Masivo
/
Autoexamen
/
Servicios de Salud Rural
/
Infecciones por Papillomavirus
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Adult
/
Female
/
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Reprod Med
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos