[The relationship between the degradation of actin and the postmortem interval in rats].
Fa Yi Xue Za Zhi
; 24(3): 165-7, 171, 2008 Jun.
Article
en Zh
| MEDLINE
| ID: mdl-18709847
ABSTRACT
OBJECTIVE:
To observe the degradation of actin in cardiac muscle, brain and skeletal muscle of rats after death and to find an objective parameter interval (PMI) estimation.METHODS:
Twenty eight clear Sprague Dawley rats put into an artificial climate incubator (set at 20 degrees C) for 0, 24, 48, 72, The actin contents in the above tissues were quantitated by Western-blot Pro Plus 5.0 image analysis system, and were then statistically analyzedRESULTS:
Actin content in all these tissues decreased gradually with prolonged differences between the groups was statistically significant (P < 0.05), with fastest, then the lung, the spleen, the liver, the kidney, the cardiac muscle order. There was a strong correlation between actin degradation and determination (R2) exceeded 0.75 in all these tissues.CONCLUSION:
degradation, the actin contents in cardiac muscle, liver, spleen, lung, kindey, rats decreased gradually with prolonged PMI, which may potentially be PMI estimation.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cambios Post Mortem
/
Encéfalo
/
Actinas
/
Patologia Forense
/
Miocardio
Límite:
Animals
Idioma:
Zh
Revista:
Fa Yi Xue Za Zhi
Asunto de la revista:
JURISPRUDENCIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
China