Predictive value of mild cognitive impairment for dementia. The influence of case definition and age.
Dement Geriatr Cogn Disord
; 27(2): 173-81, 2009.
Article
en En
| MEDLINE
| ID: mdl-19202336
ABSTRACT
BACKGROUND/AIMS:
In population studies, different mild cognitive impairment (MCI) definitions have been used to predict dementia at a later stage. This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated.METHODS:
This study was conducted as part of an ongoing longitudinal study into the determinants of cognitive aging, the Maastricht Aging Study.RESULTS:
MCI best predicted dementia when multiple cognitive domains were considered and subjective complaints were not (sensitivity 0.66, specificity 0.78). Age had a strong influence on the sensitivity of MCI for dementia (age 60-70 years sensitivity = 0.56; age 70-85 years sensitivity = 0.70).CONCLUSION:
The inclusion of multiple cognitive domains and participants aged 70 years and older leads to the best prediction of dementia, regardless of subjective complaints.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Trastornos del Conocimiento
/
Demencia
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Dement Geriatr Cogn Disord
Asunto de la revista:
GERIATRIA
/
NEUROLOGIA
/
PSIQUIATRIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Países Bajos