Superoxide dismutases, lung function and bronchial responsiveness in a general population.
Eur Respir J
; 33(5): 986-92, 2009 May.
Article
en En
| MEDLINE
| ID: mdl-19213780
ABSTRACT
Oxidative stress is an important causative factor in the onset and progression of smoking-related lung diseases, such as chronic obstructive pulmonary disease (COPD). Superoxide dismutases (SODs) can prevent an increase in oxidative burden. A total of 1,390 subjects from the prospective Vlagtwedde-Vlaardingen cohort were genotyped for two single nucleotide polymorphisms (SNPs) in SOD2 and four SNPs in SOD3, which were further analysed for associations with the presence of bronchial hyperresponsiveness (BHR; provocative concentration causing a 10% fall in the forced expiratory volume in one second (FEV(1); PC(10)
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Superóxido Dismutasa
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Hiperreactividad Bronquial
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Polimorfismo de Nucleótido Simple
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Enfermedad Pulmonar Obstructiva Crónica
Tipo de estudio:
Etiology_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur Respir J
Año:
2009
Tipo del documento:
Article
País de afiliación:
Países Bajos