A new dicoumarin and anticoagulant activity from Viola yedoensis Makino.
Fitoterapia
; 80(5): 283-5, 2009 Jul.
Article
en En
| MEDLINE
| ID: mdl-19306914
ABSTRACT
A new dicoumarin, named as dimeresculetin (1), together with another dicoumarin, euphorbetin (2) and esculetin (3) were isolated from the ethyl acetate extract of the dried whole plants of Viola yedoensis Makino. The structure of 1 was elucidated as 7-hydroxy-6-[(6,7-dihydroxy-2-oxo-2H-1-benzopyran-5-yl)oxy]-2H-1-benzopyran-2-one on the basis of extensive NMR, as well as the other spectral analysis. Compounds 1-3 exhibited anticoagulant activities with respect to activated partial thromboplastin time (APTT), prothrombin time (PT) and thrombin time (TT).
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Umbeliferonas
/
Dicumarol
/
Extractos Vegetales
/
Cumarinas
/
Viola
/
Anticoagulantes
Límite:
Animals
Idioma:
En
Revista:
Fitoterapia
Año:
2009
Tipo del documento:
Article
País de afiliación:
China