Critical illness hyperglycemia: is failure of the beta-cell to meet extreme insulin demand indicative of dysfunction?
Crit Care
; 13(2): 129, 2009.
Article
en En
| MEDLINE
| ID: mdl-19435475
ABSTRACT
In the recent study by Preissig and Rigby in Critical Care, the authors argue that critical illness hyperglycemia in children with both respiratory failure and cardiovascular failure is due to a primary failure of the beta-cell. However, alternative explanations that the failure is secondary to an increase in insulin resistance leading to beta-cell exhaustion, or a negative impact of exogenous glucocorticoid therapy, may be equally likely.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Resistencia a la Insulina
/
Enfermedad Crítica
/
Apoptosis
/
Hiperglucemia
Límite:
Humans
Idioma:
En
Revista:
Crit Care
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos