Primary antiphospholipid antibody syndrome and autoimmune haemolytic anaemia--a rare combination.
J Pak Med Assoc
; 59(6): 413-4, 2009 Jun.
Article
en En
| MEDLINE
| ID: mdl-19534383
ABSTRACT
Primary Antiphospholipid Antibody Syndrome (PAPS) and Autoimmune haemolytic anemia (AIHA) is a very rare combination. Antiphospholipid Antibody Syndrome (APS) with underlying SLE, however, has a well documented association with Coomb's positive Auoimmune Haemolytic Anaemia. We describe a young girl with PAPS presenting with deep venous thrombosis, livedo reticularis and features of AIHA. The patient was refractory to treatment for 5 years however, her condition improved dramatically with anticoagulants, corticosteroid therapy and the addition of hydroxychloroquine and azathioprin. We have also discussed hydroxychloroquine therapy in PAPS which is not yet fully established and the probability of this patient developing other autoimmune disorders in future.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Síndrome Antifosfolípido
/
Anemia Hemolítica Autoinmune
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
J Pak Med Assoc
Año:
2009
Tipo del documento:
Article
País de afiliación:
Pakistán