MicroRNAs: new players in acute myeloid leukaemia.

Havelange, V; Garzon, R; Croce, C M

Havelange, V; Garzon, R; Croce, C M.

Afiliación

Havelange V; Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

Br J Cancer ; 101(5): 743-8, 2009 Sep 01.

Article en En | MEDLINE | ID: mdl-19672257

ABSTRACT

ABSTRACT

MicroRNAs (miRNAs) are short non-coding RNAs that have key functions in a wide array of critical cell processes, including haematopoiesis by regulating the expression of multiple genes. Aberrant miRNA expression has been described in acute myeloid leukaemia suggesting a role in leukaemogenesis. In this review we summarise the current knowledge.

Asunto(s)

Leucemia Mieloide Aguda/genética; MicroARNs/genética; MicroARNs/metabolismo; Humanos; Leucemia Mieloide Aguda/diagnóstico; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/terapia; Pronóstico

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / MicroARNs Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Br J Cancer Año: 2009 Tipo del documento: Article País de afiliación: Estados Unidos

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