Acute lymphoblastic leukaemia among Spanish children and mothers' occupation: a case-control study.
J Epidemiol Community Health
; 45(1): 11-5, 1991 Mar.
Article
en En
| MEDLINE
| ID: mdl-2045737
ABSTRACT
STUDY OBJECTIVE:
The aim was to investigate the association between mothers' occupational exposure during pregnancy and the incidence of acute lymphoblastic leukaemia in children.DESIGN:
The study was a case-control investigation. A face to face interview was used to assess exposures at work and relevant confounding variables.SETTING:
The study was community based and was carried out in five provinces of Spain.SUBJECTS:
128 cases less than 15 years of age were interviewed (91% of those eligible). Controls (one for each case) were chosen from the census lists and were matched on year of birth, sex and municipality. MEASUREMENTS AND MAINRESULTS:
Children of mothers working at home had a relative risk (RR) of 7.0 (95% CI = 1.59-30.79) of developing acute lymphoblastic leukaemia. Exposure to organic dust was associated with a RR of 5.5 (95% CI = 1.21-24.8). There was a statistically significant interaction between exposure to organic dust and working at home. The majority of women working at home were hired by local industries to sew different types of tissues (cotton, wool, synthetic fibres) on a machine.CONCLUSION:
A similar association has not been reported before if confirmed, this finding may suggest a new health concern.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Efectos Tardíos de la Exposición Prenatal
/
Exposición Profesional
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Madres
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Qualitative_research
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Pregnancy
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Epidemiol Community Health
Año:
1991
Tipo del documento:
Article
País de afiliación:
Canadá