Schizophrenia and language--shall we look for a deficit of deviance detection?
Psychiatry Res
; 178(2): 225-9, 2010 Jul 30.
Article
en En
| MEDLINE
| ID: mdl-20471102
ABSTRACT
In this article, we consider the view on schizophrenia that asserts this disease originates from a deficit in the hemispheric specialization for language. We suggest that a deficit in the hemispheric specialization for language may be a consequence of the other recently shown neurophysiological deficit of schizophrenia, namely deviance detection. We hypothesise that a deficit of deviance detection related to the dysfunction of NMDA receptors in schizophrenia leads to the abnormal interaction between the parallel and sequential streams of speech processing in the brain. This hypothesis opens perspectives for genetic, molecular and pharmacological studies of the deficit of deviance detection in schizophrenia, as reflected by event-related potentials and neuroimaging during speech processing.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Esquizofrenia
/
Lenguaje
/
Trastornos del Lenguaje
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Psychiatry Res
Año:
2010
Tipo del documento:
Article
País de afiliación:
Francia