Evaluation of supercritical fluid extraction in the pharmaceutical industry.
Biotechnol Prog
; 2(2): 73-82, 1986 Jun.
Article
en En
| MEDLINE
| ID: mdl-20568193
ABSTRACT
Various steroids precipitate from supercritical CO(2) as very small particles but still retain their crystallinity. This suggests that SCFE in this industry could be utilized as a size reduction method as an alternative to milling. The application of SCFE as a separation technique is demonstrated by the simultaneous extraction and reaction of mevinolin, a metabolite of the fungus Aspergillus terreus.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Biotechnol Prog
Asunto de la revista:
BIOTECNOLOGIA
Año:
1986
Tipo del documento:
Article