Detection of congestive heart failure in dogs by Doppler echocardiography.
J Vet Intern Med
; 24(6): 1358-68, 2010.
Article
en En
| MEDLINE
| ID: mdl-20840304
ABSTRACT
BACKGROUND:
Echocardiographic prediction of congestive heart failure (CHF) in dogs has not been prospectively evaluated.HYPOTHESIS:
CHF can be predicted by Doppler echocardiographic (DE) variables of left ventricular (LV) filling in dogs with degenerative mitral valve disease (MVD) and dilated cardiomyopathy (DCM). ANIMALS Sixty-three client-owned dogs.METHODS:
Prospective clinical cohort study. Physical examination, thoracic radiography, analysis of natriuretic peptides, and transthoracic echocardiography were performed. Diagnosis of CHF was based upon clinical and radiographic findings. Presence or absence of CHF was predicted using receiver-operating characteristic (ROC) curve, multivariate logistic and stepwise regression, and best subsets analyses.RESULTS:
Presence of CHF secondary to MVD or DCM could best be predicted by Eisovolumic relaxation time (IVRT) (area under the ROC curve [AUC]=0.97, P<.001), respiration rate (AUC=0.94, P<.001), Diastolic Functional Class (AUC=0.93, P<.001), and a combination of Diastolic Functional Class, IVRT, and respiration rate (R2=0.80, P<.001) or Diastolic Functional Class (AUC=1.00, P<.001), respiration rate (AUC=1.00, P<.001), and EIVRT (AUC=0.99, P<.001), and a combination of Diastolic Functional Class and EIVRT (R2=0.94, P<.001), respectively, whereas other variables including N-terminal pro-brain natriuretic peptide, EEa, and EVp were less useful. CONCLUSION AND CLINICAL IMPORTANCE Various DE variables can be used to predict CHF in dogs with MVD and DCM. Determination of the clinical benefit of such variables in initiating, modulating, and assessing success of treatments for CHF needs further study.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ecocardiografía Doppler
/
Enfermedades de los Perros
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Insuficiencia Cardíaca
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
J Vet Intern Med
Asunto de la revista:
MEDICINA INTERNA
/
MEDICINA VETERINARIA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos