[Salt appetite, cramps and palpitations in a 21-year old medical secretary]. / Salzhunger, Krämpfe und Palpitationen bei einer 21-jährigen Arzthelferin.
Internist (Berl)
; 52(10): 1238-42, 2011 Oct.
Article
en De
| MEDLINE
| ID: mdl-21161146
ABSTRACT
Hypokalemia is a common finding. The clinical presentation can be paralyses and cardiac arrhythmias. We present a normotensive young woman with salt appetite, cramps and palpitations. In our case report the patient shows a positive family history for hypopotassemia, a metabolic alkalosis with hypotension, and hypocalciuria with an increased urinary potassium loss. The levels of renin and aldosterone were elevated. After a negative testing for metabolites of diuretics, we obtained a positive result of the suspected SLC12A3 genetic test. This mutation leads to a failure of the thiazide-sensitive sodium-2-chloride-cotransporter, the so called Gitelman syndrome, which presents similar to a chronic thiazide therapy. The Gitelman syndrome is a rare disease with renal potassium loss and hypotension. Especially in young patients around the age of twenty or in patients with chronic intractable hypopotassemia a Gitelman syndrome should be considered.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Arritmias Cardíacas
/
Receptores de Droga
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Cloruro de Sodio Dietético
/
Simportadores
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Síndrome de Gitelman
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Hipopotasemia
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Calambre Muscular
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Female
/
Humans
Idioma:
De
Revista:
Internist (Berl)
Año:
2011
Tipo del documento:
Article