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Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice.
Doi, Shigehiro; Zou, Yonglong; Togao, Osamu; Pastor, Johanne V; John, George B; Wang, Lei; Shiizaki, Kazuhiro; Gotschall, Russell; Schiavi, Susan; Yorioka, Noriaki; Takahashi, Masaya; Boothman, David A; Kuro-O, Makoto.
Afiliación
  • Doi S; From the Departments of Pathology.
  • Zou Y; Oncology, and.
  • Togao O; Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Pastor JV; From the Departments of Pathology.
  • John GB; From the Departments of Pathology.
  • Wang L; From the Departments of Pathology.
  • Shiizaki K; From the Departments of Pathology.
  • Gotschall R; the Genzyme Corporation, Cambridge, Massachusetts 02142, and.
  • Schiavi S; the Genzyme Corporation, Cambridge, Massachusetts 02142, and.
  • Yorioka N; the Department of Advanced Nephrology, Graduate School of Biomedical Sciences, 1-2-3 Kasumi, Minami-ku, Hiroshima-shi, Hiroshima 734-8551, Japan.
  • Takahashi M; Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Boothman DA; Oncology, and. Electronic address: david.boothman@utsouthwestern.edu.
  • Kuro-O M; From the Departments of Pathology,. Electronic address: makoto.kuro-o@utsouthwestern.edu.
J Biol Chem ; 286(10): 8655-8665, 2011 Mar 11.
Article en En | MEDLINE | ID: mdl-21209102

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Factor de Crecimiento Transformador beta1 / Glucuronidasa / Riñón / Neoplasias Renales / Neoplasias Experimentales Idioma: En Revista: J Biol Chem Año: 2011 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Factor de Crecimiento Transformador beta1 / Glucuronidasa / Riñón / Neoplasias Renales / Neoplasias Experimentales Idioma: En Revista: J Biol Chem Año: 2011 Tipo del documento: Article