A novel respiratory model of infection with monkeypox virus in cynomolgus macaques.
J Virol
; 85(10): 4898-909, 2011 May.
Article
en En
| MEDLINE
| ID: mdl-21389129
ABSTRACT
Variola, the causative agent of smallpox, and the related monkeypox virus are both select agents that, if purposefully released, would cause public panic and social disruption. For this reason research continues in the areas of animal model and therapeutic development. Orthopoxviruses show a widely varying degree of host specificity, making development of accurate animal models difficult. In this paper, we demonstrate a novel respiratory infection technique that resulted in "classic" orthopox disease in nonhuman primates and takes the field of research one step closer to a better animal model.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones del Sistema Respiratorio
/
Monkeypox virus
/
Mpox
/
Modelos Animales de Enfermedad
Límite:
Animals
Idioma:
En
Revista:
J Virol
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos