Integrated biomarker responses as environmental status descriptors of a coastal zone (São Paulo, Brazil).
Ecotoxicol Environ Saf
; 74(5): 1257-64, 2011 Jul.
Article
en En
| MEDLINE
| ID: mdl-21439640
ABSTRACT
São Paulo state (Brazil) has one of the most overpopulated coastal zones in South America, where previous studies have already detected sediment and water contamination. However, biological-based monitoring considering signals of xenobiotic exposure and effects are scarce. The present study employed a battery of biomarkers under field conditions to assess the environmental quality of this coastal zone. For this purpose, the activity of CYP 450, antioxidant enzymes, DNA damage, lipid peroxidation and lysosomal membrane were analysed in caged mussels and integrated using Factorial Analysis. A representation of estimated factor scores was performed in order to confirm the factor descriptions characterizing the studied areas. Biomarker responses indicated signals of mussels' impaired health during the monitoring, which pointed to the impact of different sources of contaminants in the water quality and identified critical areas. This integrated approach produced a rapid, sensitive and cost-effective assessment, which could be incorporated as a descriptor of environmental status in future coastal zones biomonitoring.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Contaminantes Químicos del Agua
/
Monitoreo del Ambiente
/
Bivalvos
/
Sistema Enzimático del Citocromo P-450
Tipo de estudio:
Prognostic_studies
Límite:
Animals
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Año:
2011
Tipo del documento:
Article
País de afiliación:
Brasil