An assay to monitor bivalirudin levels on cardiopulmonary bypass.
Ann Thorac Surg
; 92(1): 332-4, 2011 Jul.
Article
en En
| MEDLINE
| ID: mdl-21718867
ABSTRACT
Anticoagulation therapy for cardiopulmonary bypass in patients with recently diagnosed heparin-induced thrombocytopenia can be particularly challenging. Although heparin is the standard of care, in these situations anticoagulation is achieved with alternative agents such as direct thrombin inhibitors. Therapeutic concentrations are difficult to assess with direct thrombin inhibitors, and their use is riddled with bleeding and thrombotic complications. We report the successful use of a specific chromogenic antifactor IIa assay in a patient with heparin-induced thrombocytopenia who received anticoagulation therapy with bivalirudin during cardiopulmonary bypass for coronary artery bypass graft surgery.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Fragmentos de Péptidos
/
Puente Cardiopulmonar
/
Puente de Arteria Coronaria
/
Monitoreo Intraoperatorio
/
Hirudinas
/
Infarto del Miocardio
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Ann Thorac Surg
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos