Synthesis of α-S-glycosphingolipids based on uronic acids.
Org Lett
; 13(19): 5168-71, 2011 Oct 07.
Article
en En
| MEDLINE
| ID: mdl-21875123
ABSTRACT
The synthesis of S-glycosphingolipids based on uronic acids is described. These compounds are analogous to the highly immunostimulatory antigens isolated from the cell walls of bacteria of the Sphingomonas family. Key to the synthetic route is a stereoselective anomerization to give α-glycosyl thiol precursors. A route to a sphinganine precursor from pseudoephedrine glycinamide is also described.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ácidos Urónicos
/
Glicoesfingolípidos
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Irlanda