Genetic analysis of the pnp-deaD genetic region reveals membrane lipoprotein NlpI as an independent participant in cold acclimatization of Salmonella enterica serovar Typhimurium.
FEMS Microbiol Lett
; 325(1): 56-63, 2011 Dec.
Article
en En
| MEDLINE
| ID: mdl-22092862
ABSTRACT
The cold acclimatization response in many bacterial species is a tightly regulated process, which ensures the correct folding of macromolecules. In enterobacteria, this response is in part dependent on polynucleotide phosphorylase, which is encoded by the gene pnp. Based on transcriptional analysis of the pnp locus of Salmonella enterica serovar Typhimurium, we show that pnp and the adjacent membrane lipoprotein nlpI gene form an operon with both genes contributing independently to the cold acclimatization response at 15 °C. Our findings thereby define a new role for NlpI in bacterial cold acclimatization.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Salmonella typhimurium
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Proteínas Bacterianas
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Adaptación Fisiológica
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Regulación Bacteriana de la Expresión Génica
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Lipoproteínas
Idioma:
En
Revista:
FEMS Microbiol Lett
Año:
2011
Tipo del documento:
Article
País de afiliación:
Suecia