Total body irradiation and high-dose melphalan with bone marrow transplantation at Istituto Nazionale Tumori, Milan, Italy.
Radiother Oncol
; 18 Suppl 1: 105-9, 1990.
Article
en En
| MEDLINE
| ID: mdl-2247631
ABSTRACT
The technique of total body irradiation (TBI) developed at Istituto Nazionale Tumori, Milan, Italy, is described. This technique consists of i) administration of 12.5 Gy and 14.85 Gy TBI for autologous and allogeneic bone marrow transplantation respectively; ii) in all cases in vivo dosimetry of absorbed TBI dose; and iii) radiation doses to lungs higher than previously described. As of June 1988, seventeen patients with Hodgkin's disease and four with lymphoblastic lymphoma received TBI and 120-180 mg/m2 melphalan. Respiratory function was prospectively evaluated demonstrating moderate and transient reduction of pulmonary function.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad de Hodgkin
/
Irradiación Corporal Total
/
Trasplante de Médula Ósea
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Melfalán
Límite:
Adolescent
/
Adult
/
Child
/
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Radiother Oncol
Año:
1990
Tipo del documento:
Article
País de afiliación:
Italia