Breathe in and straighten your back: hypoxia, notch, and scoliosis.
Cell
; 149(2): 255-6, 2012 Apr 13.
Article
en En
| MEDLINE
| ID: mdl-22500793
ABSTRACT
In this issue of Cell, Sparrow et al. propose a new mechanism for sporadically occurring congenital scoliosis in which Notch signaling and hypoxia converge in the embryo on somite patterning via the segmentation clock. This interaction between hypoxia and a predisposed genetic background might underlie other birth defects with incomplete penetrance.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Cell
Año:
2012
Tipo del documento:
Article
País de afiliación:
Alemania