Prohemostatic treatment in cardiac surgery.
Semin Thromb Hemost
; 38(3): 237-43, 2012 Apr.
Article
en En
| MEDLINE
| ID: mdl-22510857
ABSTRACT
Cardiac surgical patients represent a unique group of patients where coagulopathy occurs due to multiple causes besides simple hemorrhagic blood loss. Hemodilution, inflammation, and hemostatic activation while on cardiopulmonary bypass all contribute to this problem and provide targets for therapeutic intervention. Current pharmacological strategies to reduce the need for allogeneic transfusions include both preemptive agents to decrease the potential for bleeding as well as prohemostatic agents to promote the coagulation process. This article will discuss pharmacological agents including antifibrinolytics, protamine, desmopressin, fibrinogen, purified protein concentrates, recombinant factor VIIa, factor XIII, and topical agents used in cardiac surgery.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hemostáticos
/
Procedimientos Quirúrgicos Cardíacos
/
Hemostasis Quirúrgica
/
Antifibrinolíticos
Límite:
Humans
Idioma:
En
Revista:
Semin Thromb Hemost
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos