Ipilimumab-induced colitis on FDG PET/CT.
Clin Nucl Med
; 37(6): 629-30, 2012 Jun.
Article
en En
| MEDLINE
| ID: mdl-22614208
ABSTRACT
A 52-year-old woman with metastatic melanoma was treated with ipilimumab. After 2 cycles of treatment, she developed watery diarrhea, sweats, and chills. An FDG PET/CT study demonstrated new FDG-avid (maximum standardized uptake value 15.6) diffuse colonic wall thickening, suggestive of ipilimumab-induced colitis. The patient was treated with systemic steroids, with subsequent resolution of her symptoms. Based on the response to steroids, the diagnosis of ipilimumab-induced enterocolitis was made. Ipilimumab may cause several immune-mediated toxicities, the most common of which is enterocolitis. Physicians interpreting FDG PET/CT examinations of patients treated with ipilimumab should be aware of these FDG-avid immune-mediated toxicities.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tomografía Computarizada por Rayos X
/
Colitis
/
Fluorodesoxiglucosa F18
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Tomografía de Emisión de Positrones
/
Imagen Multimodal
/
Anticuerpos Monoclonales
/
Antineoplásicos
Límite:
Female
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Humans
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Middle aged
Idioma:
En
Revista:
Clin Nucl Med
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos