Dosimetry of [68Ga]-labeled compounds.
Appl Radiat Isot
; 76: 70-4, 2013 Jun.
Article
en En
| MEDLINE
| ID: mdl-22884623
ABSTRACT
This review compiles and analyzes the available dosimetry data of [(68)Ga] labeled compounds. Dosimetry data are given for [(68)Ga]DOTA-NOC, TOC, TATE, and NODAGA-RGDyK. The number of PET-scans with [(68)Ga]DOTA-compounds for imaging neuroendocrine tumors is increasing because [(68)Ga] has a higher affinity to somatostatin receptors (SSTR) in comparison to comparable [(111)In]-compounds. In addition, the better image resolution of the PET images provides improved diagnostics. Despite its widespread use literature on dosimetry of [(68)Ga]-labeled radiopharmaceuticals is sparse. In some cases the description of the underlying methodology is missing or human data are gained from the extrapolation of animal experiments. More and better documented dosimetry data will further promote the use of these promising new agents.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Radiometría
/
Radiofármacos
Límite:
Humans
Idioma:
En
Revista:
Appl Radiat Isot
Asunto de la revista:
MEDICINA NUCLEAR
/
SAUDE AMBIENTAL
Año:
2013
Tipo del documento:
Article
País de afiliación:
Alemania