An efficient thiol-ene chemistry for the preparation of amphiphilic PHA-based graft copolymers.
Macromol Rapid Commun
; 33(23): 2041-5, 2012 Dec 13.
Article
en En
| MEDLINE
| ID: mdl-22961806
ABSTRACT
We present a straightforward method to prepare amphiphilic graft copolymers consisting of hydrophobic poly(3-hydroxyalkanoates) (PHAs) backbone and hydrophilic α-amino-ω-methoxy poly(oxyethylene-co-oxypropylene) (Jeffamine®) units. Poly(3-hydroxyoctanoate)-co-(3-hydroxyundecenoate) (PHOU) was first methanolyzed to obtain the desired molar mass. The amino end groups of Jeffamine were converted into thiol by a reaction with N-acetylhomocysteine thiolactone and subsequently photografted. This "one-pot" functionalization prevents from arduous and time-consuming functionalization of the hydrophilic precursor or tedious modifications of PHAs, thus simplifying the process. The amphiphilic nature of modified PHAs leads to water-soluble copolymers exhibiting thermoresponsive behavior.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polímeros
/
Compuestos de Sulfhidrilo
Idioma:
En
Revista:
Macromol Rapid Commun
Año:
2012
Tipo del documento:
Article
País de afiliación:
Francia