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[Potential use of snake venom components in cancer treatment]. / Uso potencial de componentes del veneno de serpiente en el tratamiento del cáncer.
Vivas, Dan; Inga, Rosío; Yarlequé, Armando.
Afiliación
  • Vivas D; Laboratorio de Biología Molecular, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Lima, Perú. devivasr@hotmail.com
Rev Peru Med Exp Salud Publica ; 29(3): 396-401, 2012.
Article en Es | MEDLINE | ID: mdl-23085804
Cancer can develop to the extent tumor cells grow, divide and grow into other body tissues. Integrins are a family of cell-surface heterodimeric receptors that play an important role in the development of tumor angiogenesis, growth and metastasis, thus being recognized as an attractive therapeutic target. Snake venom contains low-molecular weight peptides known as "disintegrins" that bind to integrins with high affinity, and prevent their action in cancer. In the next article, we go over the results of investigations, both in vitro and in vivo, which have shown promising results, thus revealing that the use of disintegrins could be a promising alternative for the treatment of different neoplasias.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Venenos de Serpiente / Integrinas / Desintegrinas / Neoplasias Tipo de estudio: Etiology_studies Límite: Humans Idioma: Es Revista: Rev Peru Med Exp Salud Publica Asunto de la revista: SAUDE PUBLICA Año: 2012 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Venenos de Serpiente / Integrinas / Desintegrinas / Neoplasias Tipo de estudio: Etiology_studies Límite: Humans Idioma: Es Revista: Rev Peru Med Exp Salud Publica Asunto de la revista: SAUDE PUBLICA Año: 2012 Tipo del documento: Article