Laser in treatment of laryngeal amyloidosis.

ABSTRACT

Amayloidosis is the extracellular deposition of the fibrinous protein amyloid in one or more body sites. Amyloidosis may broadly be classifed as either primary or secondary. Primary amyloidosis is idiopathic (56 %), whereas the secondary form is associated with a chronic inflammatory or infectious process (5%). Amyloidosis is also related to multiple myeloma (26%), senescence (5%) and where tumor like deposits occur in isolated organ without systemic involvement (8%). Laryngeal amyloidosis is a rare disease. Surgery has been the mainstay of treatment either endoscopicalfy or by an external neck approach. One case of laryngeal amyloidosis, treated with endolaryngeal microsurgery and carbon dioxide laser is presented with a follow up of 8 years.