Backbone resonance assignments of the outer membrane lipoprotein FrpD from Neisseria meningitidis.
Biomol NMR Assign
; 8(1): 53-5, 2014 Apr.
Article
en En
| MEDLINE
| ID: mdl-23225222
ABSTRACT
The iron-regulated FrpD protein is a unique lipoprotein embedded into the outer membrane of the Gram-negative bacterium Neisseria meningitidis. The biological function of FrpD remains unknown but might consist in anchoring to the bacterial cell surface the Type I-secreted FrpC protein, which belongs to a Repeat in ToXins (RTX) protein family and binds FrpD with very high affinity (K(d) = 0.2 nM). Here, we report the backbone (1)H, (13)C, and (15)N chemical shift assignments for the FrpD(43-271) protein that allow us to characterize the intimate interaction between FrpD and the N-terminal domain of FrpC.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteínas de la Membrana Bacteriana Externa
/
Resonancia Magnética Nuclear Biomolecular
/
Lipoproteínas
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Neisseria meningitidis
Idioma:
En
Revista:
Biomol NMR Assign
Asunto de la revista:
BIOLOGIA MOLECULAR
/
MEDICINA NUCLEAR
Año:
2014
Tipo del documento:
Article
País de afiliación:
República Checa