[Influence factors for prognosis in patients with acute oral poisoning with paraquat].

ABSTRACT

OBJECTIVE: To investigate the influential factors for the prognosis in patients with paraquat poisoning. METHODS: Retrospective analysis was performed on 40 patients with acute paraquat poisoning to evaluate serum urea nitrogen, creatinine, alanine aminotransferase, and aspartate aminotransferase levels and organ injuries. RESULTS: Among the patients, 21 had lung injury, 26 had kidney injury, 13 had multiple organ dysfunction syndrome, and 12 died. The factors associated with lung injury were kidney injury and serum urea nitrogen and creatinine levels within 24 hours after paraquat poisoning. CONCLUSION: The renal function in early stage of paraquat poisoning is related to lung injury and thus can be used asa predictor for the incidence of lung injury.