[Renal adaptation after experimental nephrectomy in animals: a review]. / Adaptation du rein après néphrectomie expérimentale chez l'animal : revue de la littérature.
Prog Urol
; 23(3): 153-64, 2013 Mar.
Article
en Fr
| MEDLINE
| ID: mdl-23446279
ABSTRACT
OBJECTIVE AND DATA-GATHERING We reviewed experimental litterature about kidney adaptation after nephrectomy in mammals. KNOWLEDGE SYNTHESIS:
Renal mass increases after nephrectomy thanks to two components, one is immediately due to the rise of glomulary capillary vascular flow, other is linked to cellular modifications with hyperplasia stage which precedes hypertrophy stage. After nephrectomy, young animals show higher renal adaptability than adults. Similarly, the sex influences the remnant kidney parenchyma volume, the increase of glomerular filtration, the hyperplasia's intensity or length, the hypertrophy's metabolic pathways and the glomerular and tubular cells' injury. There is no question that renal compensatory is regulated by hormones such as IGF-1, TGFß-1 and Ang-II.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tasa de Filtración Glomerular
/
Riñón
/
Nefrectomía
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
Fr
Revista:
Prog Urol
Asunto de la revista:
UROLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Francia