The effect of anaesthesia on the bone blood flow of the rabbit.
J Orthop Res
; 8(4): 479-84, 1990 Jul.
Article
en En
| MEDLINE
| ID: mdl-2355287
ABSTRACT
The effect of anaesthesia on the rate of bone blood flow in the rabbit was studied. Two estimates of bone blood flow were performed, using 15 microns radioactively labelled microspheres, in three groups of rabbits. The first group was anaesthetised and the interval between the two estimates was 5 min. The second group was also anaesthetised but the interval between estimates was 60 min. The third group of rabbits was conscious and the interval between the two estimates was 4 h. In the first group, small uniform falls in whole bone blood flow were observed (mean change = -5%). In the second group, larger and less predictable reductions were observed (mean change = -24%). In the third group (conscious), little change was observed in whole bone blood flow during the 4-h experiment (mean change = +7%). It is concluded that substantial falls can occur in bone blood flow in the rabbit during a 1-h anaesthetic. If bone blood flow is to be monitored under anaesthesia, then the effect of the anaesthetic on bone blood flow must be accurately defined. In conscious rabbits, estimates of whole bone blood flow performed at an interval of 4 h under control conditions will give reproducible results.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Huesos
/
Anestesia
Límite:
Animals
Idioma:
En
Revista:
J Orthop Res
Año:
1990
Tipo del documento:
Article
País de afiliación:
Reino Unido