Tuberculosis during TNF-α inhibitor therapy, despite screening.
Thorax
; 68(11): 1079-80, 2013 Nov.
Article
en En
| MEDLINE
| ID: mdl-23598710
ABSTRACT
As part of a prospective study on the safety of TNF-α inhibitor therapy after screening for and treatment of latent tuberculosis infection (LTBI), we report two patients who developed active tuberculosis (TB) infection during TNF-α inhibitor therapy, despite negative screening for LTBI. The clinical history is suggestive of a primary infection acquired during travelling to TB-endemic countries. In this lesson of the month we would like to highlight the risk of travelling to TB-endemic areas in patients treated with TNF-α inhibitor therapy. Screening for latent tuberculosis infection is not enough to prevent tuberculosis in patients treated with TNF-α inhibitor therapy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tuberculosis Pulmonar
/
Enfermedades Inflamatorias del Intestino
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Factor de Necrosis Tumoral alfa
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Huésped Inmunocomprometido
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Tuberculosis Latente
/
Anticuerpos Monoclonales
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Thorax
Año:
2013
Tipo del documento:
Article
País de afiliación:
Países Bajos