[Reprogramming equals gambling?]. / La reprogrammation, un jeu de hasard ?
Med Sci (Paris)
; 29(4): 405-10, 2013 Apr.
Article
en Fr
| MEDLINE
| ID: mdl-23621936
ABSTRACT
While somatic cell reprogramming is now part of our text books, we ignore most of the mechanisms governing this cellular transformation. The most enigmatic question is why only rare cells undergo reprogramming, and whether this is governed by stochastc or deterministic events. In the late 2012, several major studies have addressed this question through a clonal analysis of the reprogramming process in murine MEF. In this mini-review, we describe these results and discuss future perspectives based on these date to optimize and secure the derivation of iPSC.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Reprogramación Celular
/
Células Madre Pluripotentes Inducidas
Límite:
Animals
Idioma:
Fr
Revista:
Med Sci (Paris)
Asunto de la revista:
MEDICINA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Francia