[A new physiopathological classification of diabetic neuropathy]. / Bases fisiopatológicas para una clasificación de la neuropatía diabética.
Rev Med Chil
; 140(12): 1593-605, 2012 Dec.
Article
en Es
| MEDLINE
| ID: mdl-23677234
ABSTRACT
Nowadays, Diabetic Neuropathy (DN) is considered the most common cause of peripheral neuropathy in clinical practice. It can affect sensitive, motor or autonomic nerve fibers, with symmetric, asymmetric, acute or chronic presentations. Due to this variability, with multiple physiopathologic mechanisms involved, a complex clinical classification has been used until recently. The aim of this review is to present a new classification of diabetic neuropathy, based on its physiopathology. It is divided in metabolic microvascular and hypoxic, autoimmune and inflammatory, compressive, secondary to complications of diabetes and related to treatment. It must be understood that DN is not just a functional disease, but a complication of diabetes with molecular and pathological substrates caused by hyperglycemia. Therefore, normalization of blood glucose is a fundamental step towards the successful prevention and treatment of DN.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neuropatías Diabéticas
Límite:
Humans
Idioma:
Es
Revista:
Rev Med Chil
Año:
2012
Tipo del documento:
Article
País de afiliación:
Chile