Social adversity experience and blood pressure control following antihypertensive medication use in a community sample of older adults.
Int J Behav Med
; 21(3): 456-63, 2014 Jun.
Article
en En
| MEDLINE
| ID: mdl-23677855
ABSTRACT
BACKGROUND:
Psychosocial stress is a risk factor for hypertension and has been shown to affect response to treatment for psychiatric illnesses.PURPOSE:
We investigate the relationship between a history of social adversity experience and blood pressure control following antihypertensive medication use.METHODS:
A total of 1,186 participants selected from the European Prospective Investigation into Cancer-Norfolk study (531 men and 655 women, aged 42 to 80 years) had attended two health checks at which blood pressure measurements were taken; were taking antihypertensive medication at the second, but not the first health check; and had completed a questionnaire assessment of their social and psychological circumstances which included details of traumatic experiences in childhood and of adverse life events, long-term difficulties, and perceived stress in adulthood.RESULTS:
Experience of recent loss events in adulthood was associated with a smaller reduction in systolic blood pressure after starting hypertension treatment (ß = 1.78, 95 % confidence interval 0.15-3.40, per life event), independently of age, sex, preexisting health conditions, cigarette smoking history, alcohol consumption, physical activity, and obesity.CONCLUSION:
Results from this study suggest that stress caused by recent losses may be associated with reduced effectiveness of treatment for hypertension. Subject to replication, these findings may help determine the specific physiological mechanisms by which medication treatment effectiveness is affected by stress.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Estrés Psicológico
/
Presión Sanguínea
/
Adaptación Psicológica
/
Hipertensión
/
Acontecimientos que Cambian la Vida
/
Antihipertensivos
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Int J Behav Med
Asunto de la revista:
CIENCIAS DO COMPORTAMENTO
Año:
2014
Tipo del documento:
Article