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The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study.
Panoutsopoulou, Kalliope; Metrustry, Sarah; Doherty, Sally A; Laslett, Laura L; Maciewicz, Rose A; Hart, Deborah J; Zhang, Weiya; Muir, Kenneth R; Wheeler, Margaret; Cooper, Cyrus; Spector, Tim D; Cicuttini, Flavia M; Jones, Graeme; Arden, Nigel K; Doherty, Michael; Zeggini, Eleftheria; Valdes, Ana M.
Afiliación
  • Panoutsopoulou K; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Metrustry S; Department of Twin Research, King's College London, St Thomas' Hospital, London, UK.
  • Doherty SA; Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.
  • Laslett LL; Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia.
  • Maciewicz RA; Respiratory & Inflammation iMed, AstraZeneca, Mölndal, Sweden.
  • Hart DJ; Department of Twin Research, King's College London, St Thomas' Hospital, London, UK.
  • Zhang W; Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.
  • Muir KR; Centre for Epidemiology, Institute of Population Health, The Medical School, University of Manchester, Manchester, UK Health Sciences Research Institute, Warwick Medical School, University of Warwick, Coventry, UK.
  • Wheeler M; Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.
  • Cooper C; NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.
  • Spector TD; Department of Twin Research, King's College London, St Thomas' Hospital, London, UK.
  • Cicuttini FM; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Australia.
  • Jones G; Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia.
  • Arden NK; NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.
  • Doherty M; Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.
  • Zeggini E; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Valdes AM; Department of Twin Research, King's College London, St Thomas' Hospital, London, UK Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.
Ann Rheum Dis ; 73(12): 2082-6, 2014 Dec.
Article en En | MEDLINE | ID: mdl-23921993
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis de la Cadera / Proteínas / Osteoartritis de la Rodilla / Sobrepeso / Análisis de la Aleatorización Mendeliana / Interacción Gen-Ambiente Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis de la Cadera / Proteínas / Osteoartritis de la Rodilla / Sobrepeso / Análisis de la Aleatorización Mendeliana / Interacción Gen-Ambiente Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido