Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance.
Redox Biol
; 1: 115-24, 2013.
Article
en En
| MEDLINE
| ID: mdl-24024144
Palabras clave
ATF, activating transcription factor; Arylated diazeniumdiolate; DAF-FM, 4-amino-5-methylamino-2',7'-difluorofluorescein diacetate; DCF-DA, 5-(and 6)-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate; DMSO, dimethyl sulfoxide; FBS, fetal bovine serum; GSH, glutathione; GSSG, glutathione disulfide (oxidized GSH); Glutathione; HBSS, Hank's balanced salt solution; IPA, Ingenuity Pathway Analysis; JS-K, O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate; LC/MS, liquid chromatography/mass spectrometry; Leukemia; MAPK, mitogen-activated protein kinase; NAC, N-acetylcysteine; NO, nitric oxide; NSCLC, non-small cell lung cancer; Nitric oxide; PARP, poly (ADP-ribose) polymerase; RNS, reactive nitrogen species; ROS, reactive oxygen species; SAPK/JNK, stress activated protein kinase/c-jun N-terminal kinase.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Piperazinas
/
Compuestos Azo
/
Profármacos
/
Leucemia
/
Donantes de Óxido Nítrico
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Redox Biol
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos