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Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor.
Bock, Andreas; Chirinda, Brian; Krebs, Fabian; Messerer, Regina; Bätz, Julia; Muth, Mathias; Dallanoce, Clelia; Klingenthal, Dominika; Tränkle, Christian; Hoffmann, Carsten; De Amici, Marco; Holzgrabe, Ulrike; Kostenis, Evi; Mohr, Klaus.
Afiliación
  • Bock A; 1] Pharmacology & Toxicology Section, Institute of Pharmacy, University of Bonn, Bonn, Germany. [2].
  • Chirinda B; Pharmacology & Toxicology Section, Institute of Pharmacy, University of Bonn, Bonn, Germany.
  • Krebs F; Pharmacology & Toxicology Section, Institute of Pharmacy, University of Bonn, Bonn, Germany.
  • Messerer R; Department of Pharmaceutical Chemistry, Institute of Pharmacy, University of Würzburg, Würzburg, Germany.
  • Bätz J; Bio-Imaging-Center/Rudolf-Virchow-Zentrum and Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany.
  • Muth M; Department of Pharmaceutical Chemistry, Institute of Pharmacy, University of Würzburg, Würzburg, Germany.
  • Dallanoce C; Dipartimento di Scienze Farmaceutiche, Sezione di Chimica Farmaceutica 'Pietro Pratesi', Università degli Studi di Milano, Milan, Italy.
  • Klingenthal D; Pharmacology & Toxicology Section, Institute of Pharmacy, University of Bonn, Bonn, Germany.
  • Tränkle C; Pharmacology & Toxicology Section, Institute of Pharmacy, University of Bonn, Bonn, Germany.
  • Hoffmann C; Bio-Imaging-Center/Rudolf-Virchow-Zentrum and Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany.
  • De Amici M; Dipartimento di Scienze Farmaceutiche, Sezione di Chimica Farmaceutica 'Pietro Pratesi', Università degli Studi di Milano, Milan, Italy.
  • Holzgrabe U; Department of Pharmaceutical Chemistry, Institute of Pharmacy, University of Würzburg, Würzburg, Germany.
  • Kostenis E; Molecular-, Cellular- and Pharmacobiology Section, Institute of Pharmaceutical Biology, University of Bonn, Bonn, Germany.
  • Mohr K; Pharmacology & Toxicology Section, Institute of Pharmacy, University of Bonn, Bonn, Germany.
Nat Chem Biol ; 10(1): 18-20, 2014 Jan.
Article en En | MEDLINE | ID: mdl-24212135
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Acoplados a Proteínas G Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2014 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Acoplados a Proteínas G Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2014 Tipo del documento: Article