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Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A trial.
Huizinga, Tom W J; Fleischmann, Roy M; Jasson, Martine; Radin, Allen R; van Adelsberg, Janet; Fiore, Stefano; Huang, Xiaohong; Yancopoulos, George D; Stahl, Neil; Genovese, Mark C.
Afiliación
  • Huizinga TW; Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.
  • Fleischmann RM; Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.
  • Jasson M; Division of Rheumatology, Department of Medicine, University of Texas Southwestern Medical Center and Metroplex Clinical Research Center, Dallas, Texas, USA.
  • Radin AR; Department of Research and Development, Sanofi, Paris, France.
  • van Adelsberg J; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
  • Fiore S; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
  • Huang X; Department of Research and Development, Sanofi, Bridgewater, New Jersey, USA.
  • Yancopoulos GD; Department of Research and Development, Sanofi, Bridgewater, New Jersey, USA.
  • Stahl N; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
  • Genovese MC; Department of Immunology and Rheumatology, Stanford University Medical Center, Palo Alto, California, USA.
Ann Rheum Dis ; 73(9): 1626-34, 2014 Sep.
Article en En | MEDLINE | ID: mdl-24297381
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Metotrexato / Antirreumáticos / Receptores de Interleucina-6 / Anticuerpos Monoclonales Humanizados Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2014 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Metotrexato / Antirreumáticos / Receptores de Interleucina-6 / Anticuerpos Monoclonales Humanizados Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2014 Tipo del documento: Article País de afiliación: Países Bajos