[Hypothermia as a treatment for hypoxic ischemic encephalopathy after neonatal asphyxia--update].
Harefuah
; 152(9): 539-42, 563, 2013 Sep.
Article
en He
| MEDLINE
| ID: mdl-24364095
ABSTRACT
Hypoxic-ischemic encephalopathy (HIE) due to neonatal asphyxia is an important cause of irreversible bad neurodevelopmental outcomes in children. Understanding the mechanisms causing the central nervous system cell death enabled the development of new treatment strategies that may decrease the severity of neurological damage. This survey includes data on epidemiology, pathogenesis, clinical features and diagnostic criteria of HIE. We discuss the neuro-protective mechanisms of therapeutic hypothermia and provide data on clinical studies conducted to investigate the impact and safety of this treatment in newborn infants affected by HIE. In addition, other therapeutic options of neuro-protective agents are mentioned.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Asfixia Neonatal
/
Hipoxia-Isquemia Encefálica
/
Hipotermia Inducida
Tipo de estudio:
Etiology_studies
Límite:
Humans
/
Newborn
Idioma:
He
Revista:
Harefuah
Año:
2013
Tipo del documento:
Article
País de afiliación:
Israel