Parameterisation affects identifiability of population models.
J Pharmacokinet Pharmacodyn
; 41(1): 81-6, 2014 Feb.
Article
en En
| MEDLINE
| ID: mdl-24378914
ABSTRACT
Identifiability is an important aspect of model development. In this work, using a simple one compartment population pharmacokinetic model, we show that identifiability of the variances of the random effects parameters are affected by the parameterisation of the fixed effects parameters.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Dinámicas no Lineales
/
Modelos Biológicos
Idioma:
En
Revista:
J Pharmacokinet Pharmacodyn
Asunto de la revista:
FARMACOLOGIA
Año:
2014
Tipo del documento:
Article